&Parvovirus B19=Parvovirus B19 infection can present as an acute symmetric polyarthritis which may be mistaken for acute rheumatoid arthritis in the absence of rash. Arthralgia and/or arthritis is more common in adult females compared to adult males or children. Joint symptoms are usually symmetric and most frequently involve the small joints of the hands, wrists, knees, and feet. Approximately 75 percent of patients will develop a rash, although less than 20 percent will have the appearance of erythematous cheeks also known as "slapped cheek". Joint symptoms usually resolve in three weeks, although a minority of patients may develop persistent or recurring arthropathy. The arthritis associated with acute B19 infection does not cause joint destruction.