&Spondyloarthropathy=The terms spondyloarthritis, spondyloarthritides, spondyloarthropathy, and spondyloarthropathies are used to refer to a family of diseases that share certain clinical features. The most distinguishing features are inflammation of axial joints (especially the sacroiliac joints), asymmetric oligoarthritis (especially of the lower extremities), and enthesitis (inflammation at sites of ligamentous or tendon attachment to bone). Additional features are genital and skin lesions, eye and bowel inflammation, an association with preceding or ongoing infectious disorders, and a strong association with the human leukocyte antigen (HLA) B27 . The SpA family consists of the following disorders: Undifferentiated spondyloarthritis (USpA); Ankylosing spondylitis; Reactive arthritis (formerly called Reiter syndrome); SpA associated with psoriasis or psoriatic arthritis; SpA associated with Crohn's disease and ulcerative colitis; Juvenile onset spondyloarthritis. Inflammatory back pain is the most common symptom at disease onset, being present in about 70 percent of patients.